Students attend two 10-day residencies each year, in June and December, and work remotely with faculty members during the project periods separating residencies. Antioch MFA residencies are fully remote and can be attended 100 percent in person, 100 percent online, or a combination thereof. Antioch is the only low-residency MFA program with a social justice focus in the United States and requires all students to conduct an independent community focused service project known as a field study.

Genres include poetry, fiction, creative nonfiction, writing for young people, screenwriting, playwriting, and literary translation. Dual-genre degree programs are also available. Students also have the opportunity to take online electives in poetry, prose, and dramatic writing, among other offerings.

Faculty may include: Sarah Van Arsdale, Chris Belcher, Xochitl-Julisa Bermejo, Francesca Lia Block, Jaswinder Bolina, Gayle Brandeis, Chen Chen, Nikki Darling, Natashia Déon, Piotr Florczyk, Colette Freedman, Edgar Gomez, Reyna Grande, Brad Kessler, Joy Kecken, Vandana Khanna, Genevieve Hudson, Megan Kamalei Kakimoto, Sarah Manguso, Guadalupe García McCall, Tomas Moniz, Cleyvis Natera, Alistair McCartney, Morgan Parker, Victoria Patterson, Michelle Peñaloza, Carol Potter, Sharman Apt Russell, Aminah Mae Safi, Ana Maria Spagna, and others.

The program begins reviewing applications on a rolling basis in January for the Summer/Fall semester and July for the Winter/Spring Semester. Applications are accepted and reviewed until all spots are filled.